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to Bioinformatics and Computational Biology Course Page
Code: BT 301
& BT 310
Title: Bioinformatics and Computational Biology
Credits: 2 0 0 4 (BT 301)
0 0 6 6 (BT 310)
Duration: BT 301 - Tue (9 - 9.55 hrs) and Wed (10 - 10.55 hrs)
BT 310 - Thu, Fri (14 - 17.40 hrs)
Venue: 4210 ( BT 301)
Computational Lab, Department of Biotechnology
First meeting: Jul 31,
Introduction to bioinformatics; Gene bank sequence database; submitting sequences to database; Analysis of genome content and organization; Analysis of protein content and organization; Analysis of protein structures; Identification of signature motifs in proteins; Secondary structure prediction; Comparative genomics and proteomics, Basics of aligning nucleic acid and protein sequences; Phylogenetic analysis using internet; protein structure-function relationships; computational analysis of protein-ligand binding; enzyme catalysis and protein folding.
Molecular databases and their organization, Analysis of restriction sites in a known DNA fragment, design of specific PCR primers for an amplicon, homology search algorithims, multiple sequence alignment and phylogenetic analysis, gene identification strategies, identification of structural and functional motifs, visualization and analysis of protein structure, homology modeling of protein.
Suggested Texts & References:
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