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Indian Institute of Technology Guwahati

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Department of Biosciences and Bioengineering
Indian Institute of Technology Guwahati
Guwahati 781039

Telephone:
(0361) 258-2250
Fax: (0361) 258-2249
E-mail: biooff@iitg.ernet.in

 
 

DR. PRANJAL CHANDRA
M.Tech, Ph.D (PNU, South Korea)

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DR. PRANJAL CHANDRA
M.Tech, Ph.D (PNU, South Korea)
Assistant Professor
Department of Biosciences and Bioengineering
Indian Institute of Technology Guwahati
Guwahati 781039, Assam, India
 

Email: pchandra13@iitg.ernet.in
           pranjalmicro13@gmail.com

Phone: 0361-2583207

There is possibility of postdoctoral fellows in my laboratory through external funding such as; 
DST-NPDF (Opening in April 2017) and DS Kothari Post Doctoral Fellowship.
Interested candidate can send me detail CV with experience and list of publications. 
Informal discussion is encouraged.

Research Interests

We are interested to combine biotechnology, nanotechnology, material science, and electroanalytical chemistry, approaches to address problems of biomedical significance, human health, and environmental monitoring. Specifically we are interested to develop novel and commercially viable bioanayltical methods for diagnostics applications. Our major research work is focused on:

  • Clinical Diagnostics (Cancer cells, DNA, RNA, bio-markers) using electroanalytical methods such as cyclic voltammetry, chronoamperometry, impedance spectroscopy. 

  • Nano-biosensors (Aptamer, antibody, enzyme) based biological phenomenon investigation.

  • Porous silicon based label free self reporting optical nanosensors.

  • Microfluidics and Nanomachines.

Academic

Qualifications

  • Ph.D in Chemistry from Pusan National University, Busan, South Korea. Title of PhD thesis “Development of Electrochemical Biosensors for Cancer Diagnosis Based on Conducting Polymers and Nanomaterials”. (Supervisor: Prof. Yoon Bo Shim)

  • M.Tech in Biotechnology from U. P. Technical University. Title of M.Tech thesis “DNA biosensor for diagnosis of rheumatic heart disease.” (Supervisor: Prof. Ashok Kumar)

Professional Experience

  • Assistant Professor, July 2015- till date at Indian Institute of  Technology Guwahati, Guwahati, India

  • Visiting Scientist, July 2015 at Institute of Biophysio Sensor Technology, PNU, South Korea

  • Post-Doctoral Fellow, June 2014 – June 2015 at Technion - Israel Institute of Technology, Israel

  • Assistant Professor, March 2013- June 2014 Amity University, Noida, Uttar Pradesh, India

  • Lecturer (Adhoc), July 2008 - February 2009 at Amity University, Noida, Uttar Pradesh, India

Selected Publications

1.      Pranjal Chandra, Noh-Hui Bog, Ramjee Palella, Yoon Bo Shim. Ultrasensitive detection of drug  resistant cancer cells in biological matrixes using an amperometric nanobiosensor. Biosensors and Bioelectronics, Volume 70, Issue 15, 418-425, 2015. (Impact factor = 6.45).

• Appeared as "Nanosensor to diagnose drug resistant cancer cells" research highlight in Nature India EISSN: 1755-3180, A newsletter of Nature Publication group.

2.      Pranjal Chandra, Hui-Bog Noh, Yoon Bo Shim. Cancer cell detection based on the interaction between an anticancer drug and cell membrane components. RSC Chemical Communications, Cabmridge, 49, 1900-1902, 2013. (Impact factor = 6.71).

• Front cover page article in Chemical Communications, Royal Society of Chemistry (RSC), Cambridge
• This paper is the “HOT article” in RSC Chemical Communications, Cambridge and also featured as blog of
   RSC as, “A new way to look at cancer cell detection”

• This article also appeared in the RSC Chemistry World news as “A new system for cancer detection”

3.      Pranjal Chandra, Hui-Bog Noh; Mi-Sook Won, Yoon-Bo Shim. Detection of daunomycin using phosphatidylserine and aptamer co-immobilized on Au nanoparticles deposited conducting polymer. Biosensors and Bioelectronics. Vol. 26, Issue 11, 4442-4449, 2011. (Impact factor = 6.45).

4.      Hui-Bog Noh, Pranjal Chandra, Jeon Ok Moon, Yoon-Bo Shim. In vivo detection of glutathione disulfide and oxidative stress monitoring using a biosensor. Biomaterials, Vol. 33, Issue 9, 2600-2607, 2012. (Impact factor = 8.3).

5.      Pranjal Chandra, Shabi Abbas Zaidi, Hui Bog Noh, Yoon-Bo Shim. Simultaneous separation and detection of anticancer drugs in a microfluidic device with an amperometric biosensors. Biosensors and Bioelectronics, Vol. 28, Issue 1,326-332, 2011 (Impact factor = 6.45).

6.      Saurabh K Yadav, Bharati Agrawal, Pranjal Chandra, Rajendra N. Goyal. In vitro chloramphenicol detection in a Haemophilus influenza model using an aptamer-polymer based electrochemical biosensor. Biosensors and Bioelectronics, Volume 55, Issue 15, 337-342, 2014. (Impact factor = 6.45). 

Appeared as an "Antibiotic sensor" research highlight in Nature India EISSN: 1755-3180, A newsletter of Nature Publication group.

7.      Pranjal Chandra, Wei Choon Alvin Koh, Hui Bog Noh, Yoon-Bo Shim. In Vitro monitoring of i-NOS concentrations with an immunosensor: the inhibitory effect of endocrine disruptors on i-NOS release. Biosensors and Bioelectronics, Vol. 32, Issue 1,278-282, 2012. (Impact factor = 6.45).

This article has been featured in the news of High Beam Research Magazine (Europe) and also by Biotech Week Magazine (USA and Canada).

8.      Ye Zhu, Pranjal Chandra, Yoon-Bo Shim. Ultrasensitive and selective electrochemical diagnosis of breast cancer based on hydrazine-AuNP-aptamer bioconjugate. Analytical Chemistry, 85, 2, 1058–1064. 2013. (Impact factor = 5.82).

Featured as a Key Scientific Article in the Global Medical Discovery (ISSN 1929-8536), Canada.

Foreign Fellowships / Invitations / seminar delivered

1.      Received Brain Korea-21 Fellowship under Institute of Bio-Physio Sensors Technology (IBST), Pusan National University, Pusan 609-735, Republic of Korea to pursue doctoral research.

2.      Received National Research Fellowship (NRF) under the Institute of Bio-Physio Sensors Technology (IBST), Pusan National University, Pusan 609-735, Republic of Korea to pursue doctoral research. 

3.      Received award for best oral presentation in 5th BK-21 International Symposium and Workshop on Materials Chemistry, Busan, Republic of Korea 7-8 December 2010. Sponsored by Ministry of Education, Science and Technology, South Korea [MEST]. Title of talk “Selective Detection of Anticancer Daunomycin by Aptamer Immobilized on Nanostructure Conducting Polymer Film using phosphatidylserine as Signal Enhancer”.  

4.      Received award for best oral presentation in 6th BK-21 International Symposium and Workshop on Materials Chemistry, Busan, South Korea 19-21 December 2011. Sponsored by Ministry of Education, Science and Technology, South Korea [MEST]. Title of talk “An in vitro study on the toxicity effect endocrine disruptors in neuronal cell culture with an inducible nitric oxide synthase immunosensor”.  

5.      Awarded the post-doctoral research fellowship of Pusan National University, South Korea to work in the Institute of Bio-Physio Sensors Technology (IBST) under Prof. Yoon Bo Shim.

Topic: Integrated microfluidic electrochemical nanobiosensors” 

6.      Invited speaker in the 2nd International Conference & Exhibition on Biosensors & Bioelectronics" in Hilton Chicago/ Northbrook, USA on June 17-19, 2013. Title of the talk “Ultrasensitive detection of cancer cells based on anticancer-drug membrane interaction and selective silver deposition”.  

7.      Invited speaker in the BIT Congress-Europe. Major Disease Clinical summit-2013. November 5-7, Warsaw, Poland. Title: “Biosensors device in cancer diagnosis based on proteomics approach and anticancer drug-membrane interaction”. 

8.      Organizing committee member and Invited speaker of 5th International Conference and Exhibition on Analytical & Bioanalytical Techniques August 18-20, 2014, Beijing, China. 

9.      Invited speaker in the national seminar on “Recent trends in Microbiology”, 15th March 2014 organized by Department of Industrial Microbiology, DDU University Gorakhpur, (U.P), India. Title: “Electrochemical Nanobiosensor: The future of Biomedical Diagnostics”.  

10.    Invited speaker in the National Symposium on Frontiers in Modern Biology (Technology Transfer, Knowledge Translation & Social Transformation) with thematic focus on “Innovations in Science and Technology for Inclusive Development” March 24-25, 2014 organized by Indian Science Congress Association - Sagar Chapter jointly with the Department of Zoology, Dr. H. S. Gour Central University, Sagar (M.P), India. Title:  A novel aptamer based nano-bio-sensor for ultrasensitive detection of breast cancer biomarker/cells. 

11.     Delivered lecture at Institute of Nano Science and Technology, (An autonomous institute of Department of Science and Technology) Mohali, Punjab, India on May 14’ 2014.

Title: Electrochemical nanobiosensors for ultrasensitive detection of clinically important biomolecules.

12.     Awarded the post-doctoral research fellowship of Technion - Israel Institute of Technology, Israel Topic: “Label-Free Optical Porous Si-Based Biosensors for Rapid and Dual-Mode Detection of Pathogenic Bacteria. 

13.     International travel grant of 1500 USD from Technion- Israel Institute of Technology (IIT), Israel to work as a post-doctoral fellow. 

14.    Program committee member in the International Conference on Bioscience and Engineering (BIOE-2015), 23-24 January 2015, Dubai, UAE.  

15.   Delivered invited talk in the self financed short term course on “Molecular Techniques in Biotechnology” organized by Department of Biotechnology, National Institute of Technology-Allahabad (NIT-A), 16-22 January 2015.

Title: Electrochemical nanosensors: next generation tool in diagnostics and health care. 

16.    Awarded the post-doctoral research fellowship from University of Montréal, Montreal, QC, Canada to work in Laboratory of Biosensors and Nanomachines, Department of Chemistry, University of Montréal, Canada. (Declined).  

17.    International travel grant from University of Montréal, Montreal, QC, Canada to work as a post-doctoral fellow  

18.    Invited as visiting scientist at Institute of Biophysio Sensor Technology, Pusan National University, South Korea in July 2016. Delivered seminar on “Dual mode nanoporous silicon based optical biosensors”. 

19.    Travel grant of 1200 USD from Pusan National University to visit as visiting scientist in the Institute of Biophysio Sensor Technology. Host: Prof. Yoon Bo Shim. 

20.   Operating committee member of 6th International Conference and Exhibition on Analytical & Bioanalytical Techniques, September 1-3, 2015, Valencia, Spain.

 

 

 
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