Bioorganic Chemistry Research Laboratory @ IITG
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Bioorganic Chemistry Research Laboratory @ IITG
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Selected Cover Pages
                                                Publications
2017

26.    Bhattacherjee, D.; Basu, C.; Bhardwaj, Q.; Mal, S.; Sahu, S.; Sur, R.; Bhabak, K. P.*   "Design, Synthesis and Anti-Cancer Activities of Benzyl Analogues of Garlic-Derived Diallyl Disulfide (DADS)and the Corresponding Diselenides" ChemistrySelect, 2017, 2, 7399-7406.       

25.    Saha, M.; Vyas, K. M.; Martins, L. M.; Martins, N. M. R.;  Pombeiro, A. J. L.; Mobin, S. M.; Bhattacherjee, D.; Bhabak, K. P.; Mukhopadhyay, S. "Copper (II) tetrazolato complexes: Role in oxidation catalysis and protein binding" Polyhedron, 2017, 132, 53-63.


2016

24.    Bhattacherjee, D.; Bhabak, K. P.* "Atom based 3D-QSAR studies on 2,4-dioxopyrimidine-1-carboxamide analogs: Validation of experimental inhibitory potencies towards
         acid ceramidase"   Eur. J. Pharm. Sci. 201683, 8-18.       

23.    Bhabak, K. P.*; Bhowmick, D. "Synthetic strategies of gold(I)-selenolates from ortho-substituted diaryl diselenides via selenol and selenenyl sulfide intermediates" 
         Inorg. Chim. Acta2016450, 337-345.

2013

22.   Bhabak, K. P.; Hauser, A.; Redmer, S.; Banhart, S.; Heuer, D.; Arenz, C.* "Development of a Novel FRET Probe for the Real-Time Determination of     
        Ceramidase Activity"  ChemBioChem   2013,   14,   1049-1052.
        (This work has been featured on the Cover Page of the Journal)

21.    Bhabak, K. P.; Arenz, C.* "Novel Drugs Targeting Sphingolipid Metabolism", In Sphingolipids: Basic Science and Drug Development In  Handbook Exp.
         Pharmacol. Eds. Gulbins, E.; Petrache, I., Springer-Verlag Wien, 2013215,   p187-196 (Book Chapter).

20.    Bhabak, K. P.; Bhowmick, D.; Mugesh, G.* "Synthetic glutathione peroxidase mimics: Effect of nucleophilicity of the aryl thiol cofactor on the antioxidant
         activity"  Ind. J. Chem. A   2013,   52A,   1019-1025.

19.    Bhabak, K. P.; Kleuser, B.; Huwiler, A.; Arenz, C.* "Effective Inhibition of Acid and Neutral Ceramidases by Novel B-13 and LCL-464 Analogues"
     Bioorg. Med. Chem.   2013,   21,   874-882.

2012

18.    Bhabak, K. P.; Arenz, C.*"Novel Amide- and Sulfonamide-based B-13 and D-MAPP Analogues: Effect of Aromatic Substituents on the Inhibition of Acid and
         Neutral Ceramidases" Bioorg. Med. Chem.   2012,   20,   6162-6170.

17.    Bhabak, K. P.; Proksch, D.; Redmer, S.; Arenz, C.*"Novel Fluorescent Ceramide Derivatives for Probing Ceramidase Substrate Specificity"
       Bioorg. Med. Chem.   2012,   20,   6154-6161.

16.   Bhabak, K. P.;* Debasish Bhowmick "Synthesis and Structural Characterization of some Trisulfide Analogues of Thiourea-based Antithyroid Drugs."
      J. Mol. Struct.   20121022,   16-24.

15.    Bhabak, K. P.; Mugesh, G.* "Synthetic Mimics of Selenoproteins" In Selenoproteins and Mimics Eds. Liu, J.; Luo, G., Zhejiang University Press,
         Hangzhou and Springer-Verlag Berlin Heidelberg  2012,  p207-221 (Book Chapter)

2011

14.    Bhabak, K. P.; Mugesh, G.* "Gold(I)-Selenolate Complexes: Synthesis, Characterization and Ligand Exchange Reactions"
          J. Chem. Sci.   2011, 123,   783-789.

13.   Bhabak, K. P.; Satheeshkumar, K.; Jayavelu, S.; Mugesh, G.* "Inhibition of Peroxynitrite- and Peroxidase-mediated Protein Tyrosine Nitration by
        Imidazole-based Thiourea and Selenourea Derivatives" Org. Biomol. Chem.   20119,   7343-7350.

12.    Bhabak, K. P.; Mugesh, G.* "Synthesis and Characterization of Some Gold(I)-Thiolate Complexes Having N-Methylimidazole Moiety"
        Ind. J. Chem. 2011,   50A,   1303-1307.

11.    Roy, G.; Bhabak, K. P.; Mugesh, G.* "Interactions of Antithyroid Drugs and their Analogues with Halogens and their Biological Implications"
          Crystal Growth & Design,   2011, 11,   2279-2286.

10.    Bhabak, K. P.; Vernekar, A. A.; Jakka, S. R.; Roy, G.; Mugesh, G.* "Mechanistic Investigations on the Efficient Catalytic Decomposition of Peroxynitrite by
         Ebselen Analogues" Org. Biomol. Chem.  20119,   5193-5200.

09.    Bhabak, K. P.; Bhuyan, B. J.; Mugesh, G.* "Bioinorganic and Medicinal Chemistry: Aspects of Gold(I)-Protein Complexes."
        Dalton Trans.  201140,   2099-2111.

2010

08.    Bhabak, K. P.; Mugesh, G.* "Functional Mimics of Glutathione Peroxidase: Bioinspired Synthetic Antioxidants."
        Acc. Chem. Res.  201043,   1408-1419.
           (This work has been featured on the Cover Page of the Journal)

07.   Bhabak, K. P.; Mugesh, G.* "Inhibition of Peroxidase-catalyzed Protein Tyrosine Nitration by Antithyroid Drugs and their Analogues."
       Inorg. Chim. Acta  2010363,   2812-2818.

06.    Bhabak, K. P.; Mugesh, G.* "Antithyroid Drugs and their Analogues Protect Against Peroxynitrite-Mediated Protein Tyrosine Nitration -A Mechanistic Study."
      Chem. Eur. J.  201016,   1175-1185.
        (This work has been featured on the Cover Page of the Journal)

2009

05.    Bhabak, K. P.; Mugesh, G.* "Synthesis and Structure-Activity Correlation Studies of Secondary and Tertiary Amine-based Glutathione Peroxidase Mimics."
      Chem. Eur. J.   200915,   9846-9854.

04.   Bhabak. K. P.; Mugesh, G.* "A Synthetic Model for the Inhibition of Glutathione Peroxidase by Antiarthritic Gold Compounds."
      Inorg. Chem.   200948,   2449-2455.

03.    Bhabak, K. P.; Mugesh, G.* "Amide-Based Glutathione Peroxidase Mimics: Effect of Secondary and Tertiary Amide Substituents on Antioxidant Activity."
        Chem. Asian J.   20094,   974-983.

2008

02.   Bhabak, K. P.; Mugesh, G.* "A Simple and Efficient Strategy To Enhance the Antioxidant Activities of Amino-Substituted Glutathione Peroxidase Mimics."
          Chem. Eur. J.   200814,   8640-8651.

2007

01.   Bhabak, K. P.; Mugesh, G.* "Synthesis, Characterization and Antioxidant Activity of Some Ebselen Analogues."
    Chem. Eur. J.   200713,   4594-4601.


Conferences/Posters/Presentations

11.  Bhabak, K. P. (2017): Participated and presented a Poster in "INSPIRE Faculty Monitoring-cum-Interaction Meet" in the subject area of Chemical Sciences & Material Sciences at the KIIT University, Bhubaneswar, Odisha during 16-17th Jan 2017.

10.  Bhabak, K. P. (2016): Invited lecture in KIC TEQIP Short term Course on 'Recent Trends in Catalysis' in Department of Chemistry, IIT Guwahati during 13-14th May, 2016.

09. Bhabak, K. P. (2015): Participated and presented a Poster in the National Conference "New Frontiers in Chemistry -- From Fundamentals to Applications" (NFCFA2015)" in Department of Chemistry, BITS Pilani KK Birla Goa Campus during 18-19 December, 2015.

08. Bhabak, K. P. (2015): Participated and presented a Poster in "Networking-Cum-Discussion Meet" for existing INSPIRE Faculty Awardees at Tezpur University, Tezpur, Assam, India during 20-21st March, 2015.

07.    Bhabak, K. P. (2014): Participated and presented a Poster in "2nd International Symposium on Emerging Trends in Chemical and Pharmaceutical Sciences and Pharma. Chem. Expo-2014" at Indian Institute of Chemical Technology (IICT), Hyderabad, India during October 15-17, 2014.

06.    Bhabak, K. P. (2014): Participated in "16th CRSI National Symposium in Chemistry (NSC-16)" in Department of Chemistry, Indian Institute of Technology Bombay (IITB), India during 7-9th Feb 2014.

05.    Bhabak, K. P. (2013): "Real-Time Determination of Ceramidase Activity by Novel FRET-based Substrate Analogues" participated and delivered Oral Presentation in the UGC-sponsored National Symposium on "Current Trends in Chemistry" in Department of Chemistry, Sripat Singh College, Murshidabad, West Bengal, India during 23-24th Dec, 2013.

04.    Bhabak, K. P.; Arenz, C. (2012): "Development of novel fluorescent ceramide analogues for the inhibition of ceramidase activity" Presented Poster on Challenges in Bioorganic & Organic Medicinal Chemistry at 13th Tetrahedron Symposium on 26-29 June 2012, Amsterdam, Netherlands.

03.   Bhabak, K. P.; Arenz, C. (2011): "Inhibition of Ceramidase Activity by Novel B-13 Analogues" Presented a Poster at the "1st Bonn Humboldt Award Winners" Forum of the Alexander von Humboldt Foundation" at Bonn, GERMANY.

02.    Bhabak, K. P.; Mugesh, G. (2008): "Antithyroid Drugs and Related Compounds Effectively Protect Against Peroxynitrite-mediated and Peroxidase-catalyzed Nitration and Oxidation Reactions" Presented a Poster at the "10th CRSI National Symposium in Chemistry" at Indian Institute of Science (IISc), Bangalore, INDIA.

01.    Bhabak, K. P.; Mugesh, G. (2007): "Antithyroid Drugs and Related Compounds Effectively Protect against Heme-Peroxidase-catalyzed Nitration Reactions" Presented a Poster at the "Modern Trends in Inorganic Chemistry-XII (MTIC-XII) at Indian Institute of Technology (IIT) Madras, INDIA.