Dr. Ajaikumar B. Kunnumakkara

CANCER BIOLOGY LABORATORY

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     Research Articles, Reviews and Book Chapters:

       Cumulative impact factor       >500

       Total number of citations       >15,000 and h-index >40

 

     Selected articles (out of 140)

  1. Monisha J, Padmavathi G, Roy NK, Deka A, Bordoloi D, Anip A, Kunnumakkara AB. NF-κB Blockers Gifted by Mother Nature: Prospectives in cancer cell chemosensitization. Current Pharmaceutical Design 2016, Jun 9.

  2. Roy NK, Deka A, Bordoloi D, Mishra S, Kumar AP, Sethi G, Kunnumakkara AB. The potential role of boswellic acids in cancer prevention and treatment. Cancer Letters 2016; 377(1):74-86.

  3. Roy NK, Bordoloi D, Monisha J, Padmavathi G, Bordoloi D, Monisha J, Padmavathi G, Kotoky J, Golla R, Kunnumakkara AB. Specific targeting of Akt kinase isoforms: Taking the precise path for prevention and treatment of cancer. Current Drug Targets 2016, Mar 7. [Epub ahead of print]

  4. Monisha J, Roy NK, Bordoloi D, Kumar A, Golla R, Kotoky J, Padmavathi G, Kunnumakkara AB. Nuclear Factor Kappa B: A potential target to persecute head and neck cancer. Current Drug Targets 2016 Jan 31. [Epub ahead of print]

  5. Bordoloi D, Roy NK, Monisha J, Padmavathi G, Kunnumakkara AB. Multi-Targeted Agents in Cancer Cell Chemosensitization: What We Learnt from Curcumin Thus Far. Recent Pat Anticancer Drug Discov. 2014 Dec;16(2).

  6. Padmavathi G, Rathnakaram SR, Monisha J, Bordoloi D, Roy NK, Kunnumakkara AB. Potential of butein, a tetrahydroxychalcone to obliterate cancer. Phytomedicine. 2014 Dec;16(2).

  7. Khwairakpam AD,Shyamananda MS, Sailo BL, Rathnakaram SR, Padmavathi G, Kotoky J, Kunnumakkara AB. ATP Citrate Lyase (ACLY): A Promising Target for Cancer Prevention and Treatment Current Drug Targets. Current Drug Targets. 2014 Dec;16(2).

  8.  Monisha J, Padmavathi G, Kunnumakkara AB, Bordoloi D,Roy NK. Neutrophil Gelatinase-Associated Lipocalin (NGAL): A Promising Biomarker for Cancer Diagnosis and A Potential Target for Cancer Therapeutics Journal of Cell Science & Molecular Biology. Journal of Cell Science & Molecular Biology. 2014 Aug;1(2):106.

  9. Quinn B, Dallos M, Kitagawa H, Kunnumakkara AB, Memmott RM, Hollander MC, Gills JJ, Dennis PA. Inhibition of lung tumorigenesis by metformin is associated with decreased plasma IGF-I and diminished receptor tyrosine kinase signaling. Cancer Prevention Research (Phila). Cancer Prev Res (Phila). 2013 Aug;6(8):801-10.

  10. Heymach JV, Shackleford TJ, Tran HT, Yoo SY, Do KA, Wergin M, Saintigny P, Polascik TJ, Snyder DC, Ruffin MT, Yan S, Dewhirst M, Kunnumakkara AB, Aggarwal BB, Denamrk-Wahnefried W. Low-fat diet is associated with reduced plasma levels of NF-kB-regulated inflammatory cytokines and angiogenic factors in men with prostate cancer. Cancer Prevention Research, 2011;4(10):1590-8.

  11. Garg AK, Jhingran A, Klopp AH, Aggarwal BB, Kunnumakkara AB, Broadus RR, Eifel PJ, Buchholz TA. Expression of Nuclear Transcription Factor Kappa B in locally advanced human cervical cancer treated with definitive chemoradiation. International Journal of Radiation Oncology . Biology . Physics. 2010;78(5):1331-6.

  12. Kunnumakkara AB, Sung B, Ravindran J, Diagaradjane P, Dey S, Koca C, Yadav VR, Tong Z, Gelovani JG, Guha S, Krishnan S and Aggarwal BB. g-tocotrienol inhibits pancreatic tumors and sensitizes them to gemcitabine treatment by modulating the inflammatory microenvironment. Cancer Research, 2010;70(21):8695-705.

  13. Kunnumakkara AB, Diagaradjane P, Anand P, Harikumar KB, Deorukhkar A, Gelovani J, Guha S, Krishnan S, Aggarwal BB. Curcumin potentiates the antitumor effects of capecitabine, reverses resistance and inhibits metastases of colon cancer in orthotopic mouse model: Role of NF-kB and NF-kB-regulated gene products. International Journal of Cancer. 2009;125(9):2187-2197.

  14. Kunnumakkara AB, Anand P, Aggarwal BB. Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins. Cancer Letters. 2008;269(2):199-225 (review).

  15. Anand P, Kunnumakkara AB, Sundaram C, Harikumar KB, Tharakan ST, Lai OS, Sung B, Aggarwal BB. Cancer is a preventable disease that requires major lifestyle changes. Pharmaceutical Research. 2008;25(9):2097-116 (review).

  16. Dhillon N, Aggarwal BB, Newman R, Wolff R, Kunnumakkara AB, Abbruzzese J, Ng C, Badmaev V, Kurzrock R, Phase II Trial of curcumin, an NF-kappaB inhibitor, in patients with advanced Pancreatic Cancer Clinical Cancer Research, 2008;14(14):4491-9.

  17. Kunnumakkara AB, Diagaradjane P, Guha S, Deorukhkar A, Shentu S, Aggarwal BB, Krishnan S, Curcumin Sensitizes Human Colorectal cancer xenografts in nude mice to g-radiation by targeting NF-kB-regulated gene products, Clinical Cancer Research. 2008;14(7):2128-36 (Cover page).

  18. Anand P, Kunnumakkara AB, Newman RA, Aggarwal BB. Bioavailability of curcumin: Problems and promises. Molecular Pharmaceutics, 2007;4(6):807-18 (review).

  19. Lin YG, Kunnumakkara AB, Nair A, Merritt WM, Han LY, Armaiz-Pena GN, Kamat AA, Spannuth WA, Gershenson DM, Lutgendorf SK, Aggarwal BB, Sood AK.  Curcumin inhibits tumor growth and angiogenesis in ovarian carcinoma by targeting the nuclear factor-kappaB pathway. Clinical Cancer Research. 2007;13(11):3423-30 (Cover page).

  20. Kunnumakkara AB, Guha S, Krishnan S, Diagaradjane P, Gelovani J, Aggarwal BB.  Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products. Cancer Research. 2007;67(8):3853-61.

      Magazine Articles

Kunnumakkara AB and Aggarwal BB. Chemoprevention of GI Cancers with Dietary agents: Are We There Yet? American Gastroenterological Association (AGA)    perspectives.  Jan, 2008.

 

      Books

1.  Molecular Targets and therapeutic uses of spices -Modern Uses for Ancient Medicine.
     (World Scientific Publications, Hackensack, NJ 07601 USA, published in June, 2009).
      http://www.worldscientific.com/worldscibooks/10.1142/7150

 

2.  Anticancer Properties of Fruits and Vegetables: A Scientific Review.

     (World Scientific Publications, Hackensack, NJ 07601 USA, published in December, 2014).

     http://www.worldscientific.com/worldscibooks/10.1142/8823

 

3.  Fusion Genes and Cancer

     http://www.worldscientific.com/worldscibooks/10.1142/10306

4.  Cancer Cell Chemoresistance and Chemosensitization                                                                                                                                               http://www.worldscientific.com/worldscibooks/10.1142/10407

Copyright: Indian Institute of Technology Guwahati (IITG), Assam, India