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Publications

Journal Papers

1. Debamitra Chakravorty, Sanjukta Patra. Significance of Lipolytic Enzymes in Pathogenesis and Treatment of Neglected Diseases. Current Protein and Peptide Science, 2016, 17, 000-000. (Accepted).

2. Debamitra Chakravorty, Mohd Faheem Khan and Sanjukta Patra. Thermostability of Proteins Revisited Through Machine Learning Methodologies: from Nucleotide Sequence to Structure. Current Biotechnology, 2016.Volume 5 (E-pub ahead of print).

3. Bhaskar Das, Tapas K Mandal, Sanjukta Patra. Biodegradation of phenol by a novel diatom BD1IITG-kinetics and biochemical studies. International Journal of Environmental Science and Technology, 2015, Spinger, International Journal of Environmental Science and Technology. February 2016, Volume 13, Issue 2, pp 529-54. IF – 2.19

4. Bhaskar Das, Tapas K Mandal, Sanjukta Patra. A comprehensive study on Chlorella Pyrenoidosa for phenol degradation and its potential applicability as biodiesel feedstock and animal feed. Applied Biochemistry and Biotechnology, 2015, Springer, 176, 1382-1401. IF – 1.73

5. Parameswaran Saravanan, Sanjukta Patra. Discovery of Potential Dual Inhibitors Against Lipases Rv0183 and Rv3802c for Tuberculosis Therapeutics. Letters in Drug Design & Discovery 13(2):185-195. November 2015. 13(2):185-195. IF - 0.77

6. Parameswaran Saravanan, Vikash Kumar Dubey, Sanjukta Patra. Journal of molecular modeling.Emulating structural stability of Pseudomonas mendocina Lipase: in silico Mutagenesis and Molecular Dynamics Studies. (Oct 2014) 20(11):2501. IF-1.74

7. Saravanan Parameswaran, Prakash Saudagar, Vikash Kumar Dubey and Sanjukta Patra. Discovery of novel inhibitors targeting LdLip3 Lipase to combat Leishmaniasis. Journal of Molecular Graphics & Modelling 2014 January 29, 49: 68-79. IF-2.325

8. Sonali Seth, Debamitra Chakravorty, Vikash K Dubey, Sanjukta Patra. Plant lipase research-challenges encountered. Protein Expression and Purification. 95 (2014) 13–21. Accepted. IF-1.507 (Most downloaded article in last 90 days)

9. Nivedita Singh, Sanjukta Patra. Phosphodiesterase 9: Insight of protein structure and role in therapeutics. Life Sciences 106 (2014) 1–11. I.F-2.704

10. Parameswaran Saravanan, Hindupur Avinash, Vikash Kumar Dubey, Sanjukta Patra. Targeting essential cell wall lipase Rv3802c for potential therapeutics against tuberculosis. Journal of Molecular Graphics and Modelling. 2012. Volume 38:235-42 IF 2.33

11. Debamitra Chakravorty, Sumit Singh, Parameswaran Saravanan, Sanjukta Patra. Design of lead peptide drugs from mushroom targeting cysteine proteases. Journal of Medicinal Chemistry Research. 2012. Volume 22, Issue 4(2013), 2038-2049. IF 1.271

12. Debamitra Chakravorty, Saravanan Parameswaran, Vikash Kumar Dubey and Sanjukta Patra. Unraveling the rationale behind organic solvent stability of lipases. Appl Biochem Biotechnol. 2012, 167:439-461. IF 1.943.

13. Parameswaran Saravanan, Vikash Kumar Dubey and Sanjukta Patra. Potential Selective Inhibitors against Rv0183 of Mycobacterium tuberculosis Targeting Host Lipid Metabolism. Chemical Biology and Drug Design. 2012 Volume 79, Issue 6, pages 1056–1062, IF 2.282

14. V. R. Sarath Babu & M. S. Thakur and Sanjukta Patra. Effect of Physicochemical Parameters on Enzymatic Biodecaffeination During Tea Fermentation. Appl Biochem Biotechnol (2012) 166 (1) 112-126. IF 1.879.

15. Debamitra C, Saravanan P, Dubey VK and Sanjukta Patra. In Silico Characterization of Thermostable Lipases. Extremophiles (2010) 15, 89-103. IF 2.941.

16. Bankapallai Leela Krishna, Abhay Narain Singh, Sanjukta Patra and Vikash Kumar Dubey. Purification, Characterization and Immobilization Of Urease from Momordica charantia seeds, Process Biochemistry, 2011, 2011, 46 , 1486-1491. IF 2.648.

17. Saravanan P, Santhosh KV, Mohan CG, Dubey VK and Sanjukta Patra. Mitogen-activated Protein Kinase 4 of Leishmania Parasite os Therapeutic Target. European J Med Chem (2010) 45, 5662-5670. IF 3.193.

18. Saravanan P, Dubey V.K and Sanjukta Patra. In silico Characterization of Thermoactive, Alkaline and Detergent-Stable Lipase from Staphylococcus aureus strain. In Silico Biology. (2010) 10 (5, 6) 265-276.

19. Saravanan P, Alpana A.T and Sanjukta Patra. Deciphering Role of Amino Acids for the Stability of Staphylococcus aureus Lipase (SAL3). Interdiscip Sci Comput Life Sci (2010) 2, 271-279.

20. Deb K. Das, Satavisha Sarkar, Abu T. Khan, Parameswaran Saravanan and Sanjukta Patra. Synthesis of fused tetrahydropyrido[2,3-c]coumarin derivatives as potential inhibitors for dopamine d3 receptors, catalyzed by hydrated ferric sulfate. RSC Advances. IF 2.562

21. Priyamvada Jain, Babina Chakma, Sanjukta Patra, Pranab Goswami. Potential biomarkers and their applications for rapid and reliable detection of malaria. BioMed Research International. BioMed Research International, vol. 2014, Article ID 852645,20 pages, 2014. doi:10.1155/2014/852645. IF 2.88

22. Neeraj Katiyar, L. Sagaya Selvakumar, Sanjukta Patra and Munna Singh Thakur. Gold nanoparticles based colorimetric aptasensor for theophylline. Analytical Methods. 2012 Volume 5 (3) Nov 10. IF 1.547

23. Debalina Chakraborty, Parameswaran Saravanan, Sanjukta Patra and Vikash Kumar Dubey. Studies on ornithine decarboxylase of Leishmania donovani: Structure modeling and inhibitor docking. Medicinal Chemistry Research. IF 1.271

24. Anil K Shukla, Sanjukta Patra and Vikash Kumar Dubey. "Evaluation of selected antitumor agents as subversive substrate and potential inhibitor of trypanothione reductase: An alternative approach for chemotherapy of Leishmaniasis". Molecular and Cellular Biochemistry. (2011) 352, 261-270. IF 2.168

25. Anil K Shukla, Sanjukta Patra, Vikash Kumar Dubey. Biophysical and folding parameters of trypanothione reductase from Leishmania infantum. Applied Biochemistry and Biotechnology. (2011) 165, 13-23. IF 1.879

26. Anil K Shukla, Sanjukta Patra and Vikash Kumar Dubey. Deciphering molecular mechanism underlying antileishmanial activity of Nyctanthes arbortristis, an Indian medicinal plant. Journal of Ethnopharmacology. (2011) 134, 996-998. IF 2.466.

27. Anil K Shukla, Bishal K Singh, Sanjukta Patra, Vikash Kumar Dubey. Rational approaches for drug designing against leishmaniasis. Applied Biochemistry and Biotechnology. (2010) 160, 2208-2218. IF 1.879.

28. Anil Kumar Shukla, Sanjukta Patra and Vikash Kumar Dubey. Iridoid glucosides from Nyctanthes arbortristis result in increased Reactive Oxygen Species (ROS) and cellular redox homeostasis imbalance in Leishmania parasite. European Journal of Medicinal Chemistry, 2012, Vol 54 , 49-58. IF 3.193.

29. Anil Kumar Shukla, Sanjukta Patra and Vikash Kumar Dubey. PEGylated nanospheres encapsulating antileishmanial drugs for their specific macrophage targeting, reduced toxicity and enhanced activity. Vector-Borne and Zoonotic Diseases, 2012. 12, 953-60. IF 2.437

30. Abu T. Khan,* Mohan Lal, Prasanta Ray Bagdi, Sidick Basha R, Parameswaran Saravanan, Sanjukta Patra. Nickel (II) chloride hexahydrate (NiCl2.6H2O) as an efficient and useful catalyst for one-pot four-component reaction: Synthesis of tetra-substituted pyrroles, a potential phosphodiesterase inhibitor. Tetrahedron Letters 53 (2012) 4145–4150. IF 2.588.

31. V.R. Sarath Babu, Sanjukta Patra, N. G. Karanth, M.A. Kumar and M.S. Thakur. Development of a Biosensor for caffeine. Analytica chimica Acta. (2007) 582 (2) 329-334. IF 4.310.

32. V.R. Sarath Babu, Sanjukta Patra, N. G. Karanth, M.A. Kumar and M.S. Thakur. Degradation of caffeine by Pseudomonas alcaligenes CFR 1708 . Enzyme and Microbial Technology. (2005) 27, 617-624. IF 2.287.

33. Vineet Kumar, Sanjukta Patra, Anita Rani, S.P. Tiwari. Indian soybean varieties with low levels of lipoxygenase isozymes. Journal of Food Science and Technology. (2002) 39 (1) 74-75. IF 0.477

BOOK CHAPTERS

6. Nitendra Kumar, Bhaskar Das, Sanjukta Patra*. Drug resistance in tuberculosis: Nanomedicines at rescue. In: Grumezescu AM (ed) Nanostructures in therapeutic medicine, Elsevier. Volume 2: Nanostructures for Antimicrobial Therapy. (Revision).

5. Bhaskar Das, Sanjukta Patra*. Antimicrobials: Meeting challenges of antibiotic resistance through nanotechnology. In: Grumezescu AM (ed) Therapeutic Nanostructures, Elsevier (Accepted for publication). Therapeutic Nanostructures. Volume III: Antimicrobials.

4. Manashjit Gogoi1, Nitendra Kumar2, Sanjukta Patra2* Multifunctional magnetic liposomes for cancer imaging and therapeutic applications. Therapeutic Nanostructures. Volume II: Drug Delivery.(Communicated)

3. Advance Techniques in Enzyme research, by Debamitra Chakravorty and Sanjukta Patra in Advances in Enzyme Biotechnology (Springer) Ed. P. Shukla. 2013. Pages 89-109.

2. Debamitra Chakravorty, Ashwini Shreshtha, V.R.Sarath Babu and Sanjukta Patra*. Chapter 1. Molecular evolution of extremophiles. Chapter 1, in Exremophiles: Sustainable resources and Biotechnological Implications. Ed. Singh OV; Wiley-Blackwell; USA.2012.

1. Debamitra Chakravorty and Sanjukta Patra*. Attaining extremophiles and extremolytes: methodologies and limitations. Chapter 2, in Exremophiles: Sustainable resources and Biotechnological Implications. Chapter 2. Ed. Singh OV; Wiley-Blackwell; USA.2012.

CONFERENCE PUBLICATIONS

45. Characterization of phenol degradation by a novel diatom species BD1IITG isolated from petroleum refinery wastewater.Proceeding of National Conference on sustainable development of environmental systems. Pg-30. IIT Guwahati. June 20-21, 2014. Oral Presentation. Bhaskar Das, Tapas K Mandal, Sanjukta Patra.

44. Analytical Hierarchical Process Ranking Method to Distinguish Thermostable and Mesostable Proteins. Debamitra Chakravorty, Sanjukta Patra . Symposium cum Workshop on Advances in Computational Biology and Computer Aided Drug Design, Bioinformatics Infrastructure Facility, IIT Guwahati, Guwahati 2015. (Oral presentation).

43. Debamitra Chakravorty, Sanjukta Patra . A two-step method to generate protein thermostable mutants for industrial applications. (oral presentation) GBP`s Talent Search contest on Innovative Research Ideas Leading To Entrepreneurial Venture In Biotechnology and AlliedAreas. Guwahati,20th -21st November, 2015. (Awarded 4th prize).

42. Adopting analytical hierarchical process to rank features contributing towards organic solvent stable proteins. 82nd Meeting of Society of Biologial Chemists. University of Hyderabad, Hyderabad, India. 2nd to 5th December 2013. Sonali Seth, Debamitra Chakravorty, Sanjukta Patra .

41. Biodegradation of phenol by microalgae.Proceeding of National Conference on sustainable development of environmental systems. Pg-75. IIT Guwahati. June 20-21, 2014.Bhaskar Das, Gowtham Selvaraj, Tapas K Mandal., Sanjukta Patra.

40. Isolation and growth kinetics of a phenol degrading novel diatom species BD1IITG. 64th Canadian Chemical Engineering Conference. Niagara Falls, Canada, October 19-22, 2014. (Oral Presentation).Bhaskar Das, Tapas K Mandal, Sanjukta Patra.

39. Performance evaluation of phenol degradation by Chlorella pyrenoidosa in nutrient sufficient media and refinery wastewater through kinetic modeling. 64th Canadian Chemical Engineering Conference. Niagara Falls, Canada, October 19-22, 2014. (Oral Presentation). Bhaskar Das, Tapas K Mandal, Sanjukta Patra.

38. Mechanism of phenol degradation in Chlorella Pyrenoidosa. Asian Plant Science Conference. 1-3rd November 2014, Lumbini, Nepal. (Oral Presentation). Bhaskar Das, Sanjukta Patra.

37. Recent advances in algal biodiesel production. Asian Plant Science Conference. 1-3rd November 2014, Lumbini, Nepal. (Oral Presentation). Gowtham Selvaraj, Bhaskar Das, Sanjukta Patra .

36. Characterization of phenol degradation in microalgae. Research Scholars Day 2015, 19th January, IIT Guwahati. (Oral Presentation). Bhaskar Das, Tapas K Mandal, Sanjukta Patra .

35. Kinetics and enzymatic mechanism of microalgal phenol degradation.Proceedings of National Conference on Challenges in Environmental Research, Pg. 30, June 4-6, 2015, IIT Guwahati. (Oral Presentation). Bhaskar Das, Tapas K Mandal, Sanjukta Patra .

34. Predicting protein thermostability from sequence to structure. Advances in Computational Biology and Computer Aided Drug Design. 24th-26th Jun 2015. Department of Biosciences and Bioengineering, IIT Guwahati, Guwahati. Mohd Faheem Khan. Participation: Young Investigators Oral Talk.

33. In silico prediction of protein stability at extreme temperature through machine learning methodologies. Exploring Mechanisms in Biology: Theory and Experiment. 25th - 27th November, 2015. Bioinformatics Institute (BII) A*STAR, Singapore. Mohd Faheem Khan, Debamitra Chakravorty, Sanjukta Patra

32. An insight into the behavior of psychrophilic and thermophilic proteins. MCB75: from Molecules to Organisms. 11th - 14th December, 2015. Department of Microbiology and Cell Biology, IISc Bangalore, Bangalore. Mohd Faheem Khan, Debamitra Chakravorty, Sanjukta Patra

31. Sonali Seth, Debamitra Chakravorty, Sanjukta Patra . Adopting analytical hierarchical process to rank features contributing towards organic solvent stable proteins. 82nd Meeting of Society of Biologial Chemists.University of Hyderabad, Hyderabad, India. 2nd to 5th December 2013.

30. Bhaskar Das, Tapas K Mandal, Sanjukta Patra . Phenol degradation by Chlorella Pyrenoidosa”, International Conference on Algal Biorefinery: A potential Source of Food, Feed, Biochemicals,Biofuels and Biofertilizers. January 10-12, 2013, IIT Kharagpur.

29.P.Saravanan, Sanjukta Patra . True Lipase Database. European Conference on Computational Biology. ECCB 2012. 9-14 Sep 2012. Basel Switzerland.

28 .P.Saravanan, Sanjukta Patra. Identification of potential multi-target inhibitors for tuberculosis. International conference on Biomolecular forms and functions organized by Indian Institute of Science. 8-11 Jan 2013.

27. Nivedita Singh and Sanjukta Patra . Designing and in-silico analysis of xanthine based inhibitors targeting phosphodiesterase. International conference on health, environment and industrial biotechnology: Biosangam 2013.

26. V.R.Sarath Babu, M.S.Thakur, Sanjukta Patra. Structure prediction of caffeine demethylating enzyme from Pseudomonas alcaligenes ICBBT 2012. 26-28 February 2012. Singapore.

25. Parameswaran Saravanan, Vikash Kumar Dubey, Sanjukta Patra. Potential inhibitors targeting LdLip3 to combat Leishmaniasis. Indian Biophysical Meeting organized by University of Madras in 19-21 Jan 2012.

24. P.Saravanan, Sanjukta Patra. Reversible Inhibitors To Combat Tuberculosis: Homology Modeling, Virtual Screening And Comparative Docking Studies. OSCAT 2012. 22-25th February Institute of Microbial Technology Chandigarh.

23. Parameswaran Saravanan, Avinash Hindupur, Vikash Kumar Dubey, Sanjukta Patra Targeting essential cell wall lipase rv3802c to combat tuberculosis: homology modeling, virtual screening and comparative docking studies. OSCAT 2012. 22-25th February 2012 IMTECH Chandigarh.

22. Bhaskar Das, Tapas K Mandal, Sanjukta Patra. Pathway of  phenol degradation in Chlorella Pyrenoidosa. Young ecologists talk and interact. Indian Institute of Technology, Guwahati, India. December 13-15, 2011.

21. Abhijith K.S., Sanjukta Patra, M.S. Thakur. Interaction of Gold Nanoparticles with Biological Molecules. ICANN 2011, 8-10 Dec 2011, IIT-Guwahati, India.

20. Debamitra Chakravorty, Sumit Singh, Sanjukta Patra. Design of peptide inhibitors for cysteine proteases. Society of Biological Chemists 12-15th Nov 2011. CIMAP Lucknow, India.

19. Sonali Seth, Debamitra Chakravorty, Sanjukta Patra. An insight into pH stability of enzymes. Society of Biological Chemists 12-15th Nov 2011. CIMAP Lucknow, India.

18. Debamitra Chakravorty, Sanjukta Patra. The rationale behind organic solvent stability of lipases: an in silico approach. Society of Biological Chemists 12-15th Nov 2011. CIMAP Lucknow, India.

17. Bhaskar Das, Tapas K Mandal, Sanjukta Patra. Pathway of phenol degradation in Chlorella Pyrenoidosa, Young ecologists talk and interact 2011, December 13-15, Indian Institute of Technology, Guwahati, India.

16. Abhijith K.S., Sanjukta Patra, M.S. Thakur. Interaction of Gold Nanoparticles with Biological Molecules. ICANN 2011, 8-10 Dec 2011, IIT-Guwahati, India

15. Chakravorty D, Singh SK, Sanjukta Patra. In silico characterization of mechanism of action of cysteine protease inhibitors from mushroom. Annual conference AMI, Birla Institute of Technology, Ranchi, 14-17 Dec, 2010.

14. Raveendran A, Chakravorty D, Sanjukta Patra. Analysis of bactericidal activity from mushroom extract of North East India. Annual conference AMI, Birla Institute of Technology, Ranchi, 14-17 Dec, 2010.

13. Saravanan Parameswaran, Sanjukta Patra. In silico characterization and virtual screening of Rv0183, a monoglyceride lipase from Mycobacterium tuberculosis. Annual Meeting of the Society of Biological Chemists, (India). Indian Institute of Science, Bangalore, December 13-15, 2010.

12. Saravanan Parameswaran, Alpana Thorat, Debamitra Chakravorty, Sanjukta Patra. In Silico Characterization and Structural Modeling of Thermoactive and Alkaline Staphylococcus Lipase. Asia-Pacific Bioinformatics Conference, NCBS, Jan 18-21, 2010.

11. P. Saravanan, Alpana Ankush Thorat, Sanjukta Patra. Deciphering role of Amino Acids for the stability of lipase. International conference on Bioinformatics, Surat, 25-28th March 2010.

10. Chakravorty D, Saravanan P, Alpana Thorat, Ayan Sadhukhan, Sanjukta Patra. Thermostable lipases and their in silico characterization. 48th Annual conference AMI National Chemical Laboratory, Pune, December 15-19, 2009.

9. V.R. Sarath Babu, Sanjukta Patra, M.S.Thakur and N.G.Karanth. A biosensing method for detection of caffeine based on fluorescence. National symposium on sensors and Instrumentation in Food Processing held at CFTRI, Mysore Jan 20-21, 2006.

8. M.S.Thakur, Sanjukta Patra.  Caffeine metabolism – a comparative study on enzymes using Biomodeling. National Workshop on Biomodeling, Biosensors and BIOMEMS” organized by Teamtech-2006, held at IISc Bangalore from 28th Feb-2nd March 2006.Best paper award.

7. V.R. Sarath Babu, Sanjukta Patra, N. G. Karanth, M. A. Kumar and M. S. Thakur, Development of a Biosensor for caffeine. 9th World congress on Biosensors at Toronto, Canada, 10-12th May 2006.

6. M.S.Thakur, Sanjukta Patra. Utilization of coffee processing wastes for value addition. Seminar on “Food Processing Industries – Role of Quality and Management March 20-21, 2006” at Institute of Engineers, Bangalore.

5. V.R. Sarath Babu, Sanjukta Patra, M.S.Thakur. Quantum dots as probes for localization of enzymes. National symposium on sensors and Instrumentation in Food Processing” held at CFTRI, Mysore Jan 20-21, 2006.

4. Sanjukta Patra, M.S.Thakur.Biotransformation of 1,3,7 trimethyl xanthine to theophylline. 46th annual conference of “Association of Microbiologists of India” held at Osmania University, Hyderabad Dec 8-10, 2005. Best Poster award.

3. Sanjukta Patra, M.S.Thakur. Microbes in Material Science–Potential untapped. Competition organized by Association of Microbiologists of India June 2004. Best oral presentation Award.

2. V.R. Sarath Babu, Sanjukta Patra, M.S.Thakur. Utilization of coffee processing waste for enzyme production by solid-state fermentation. 13th “Indian Convention of Food Scientists and Technologists”, held at DFRL and CFTRI, Mysore Dec 9-10, 2004.

1. Sanjukta Patra, M.S.Thakur. Studies on a biotechnological method for decaffeination using immobilized microbial cells. 5th “International Food Convention”, held at CFTRI, Mysore Dec 7-11, 2003. Best Poster Awarded.

 

PATENTS

1. Sanjukta Patra, M.S.Thakur, N.G.Karanth. A process for microbial biotransformation of caffeine to theophylline. Granted Application, Patent Number : 250721.

2. Vikash Kumar Dubey, Sanjukta Patra, Anil Kumar Shukla and Santhosh Kannan. Iridoid glucosides from Nyctanthes arbortristis as new class of inhibitor of Trypanothione reductase of Leishmania parasite. (306/KOL/2010).