MALARIA RESEARCH LAB

Publications: 84

Book chapters: 2

Total Number of Citations: 1803; H-Index: 25; I10 Index=44

2020

1. Anupriya Mehra, Balaji, SN and Trivedi, V* (2020) Haemozoin is a potential threat in cerebral malaria pathology through induction of RBC-EC cytoadherence. Acta Tropica (In Press)
2. Anil Kumar D., Srivastava, D., Sahasrabuddhe, AA., Habib, S and Trivedi, V* (2020) Plasmodium falciparum FIKK 9.1 is a monomeric serine-threonine protein kinase with features to develop anti-malarials. Chem Bio Drug Res.
3. Jha, S., Trivedi, V*. (2020) Biophysical Characterization of Manikya Bhasma and its role in affecting Cancer cells viability through induction of Apoptosis. Journal of Ayurveda and Integrative Medicine (in press).
4. Balaji, SN., Deshmukh*, R and Trivedi V*. (2020) Severe malaria: Biology, Clinical manifestation, Pathogenesis and consequences. Journal of Vector Borne Diseases (In Press).
5. Balaji, SN., Sahasrabuddhe, AA., and Trivedi, V* (2020) Insulin signalling in RBC is responsible for growth stimulation of malaria parasite in diabetes patients. Biochemical and Biophysical Research Communications, Volume 528, Issue 3, 30 July 2020, Pages 531-537.
6. Jerath, G., Goyal, R., Trivedi, V., Santhoshkumar, TR., Ramakrishnan, V (2020) Conformationally Constrained Peptides for Drug Delivery. J peptide sciences (In Press).

2019

1. Banesh, S., Trivedi, V*. (2019) Therapeutic potentials of Scavenger receptor CD36 mediated innate immune responses against infectious and non-infectious diseases. Curr Drug Discov Technol. Aug 2019.
2. Mostakim SK, Mohammed Rafi Uz Zama Khan, Aniruddha Das, Soutick Nandi, Vishal Trivedi, and Shyam Biswas (2019) A phthalimide functionalized UiO-66 metal-organic framework for the fluorogenic detection of hydrazine in live-cells. Dalton Trans
3. Saha, Abhishek ; Pradhan, Nirmalya ; Chatterjee, Soumya ; Singh, Kumar Rakesh ; Bhattacharyya, Arindam; Trivedi, Vishal*; Manna, Debasis* (2019). Fatty-Amine-Conjugated Cationic Bovine Serum Albumin Nanoparticles for Target-Specific Hydrophobic Drug Delivery. ACS Appl. Nano Mater. 2019, 2, 6, 3671-3683
4. Jerath, G., Goyal, R., Trivedi, V., Santhoshkumar, TR., Ramakrishnan, V (2019) Syndiotactic Peptides for Targeted Delivery. Acta Biomaterialia;87: 130-139.
5. Das, A; Das, S; Trivedi, V and Biswas, S (2019). A Dual Functional MOF-Based Fluorescent Sensor for Intracellular Phosphate and Extracellular 4-Nitrobenzaldehyde. Dalton Trans., 2019, 48, 1332–1343.
6. Kumar, S and Trivedi, V* (2019). Extracellular Methemoglobin promotes Cytoadherence of Uninfected RBC to Endothelial cells: Insight into cerebral malaria pathology. Journal of Cellular Biochemistry, 2019; 120: 11140-11149.
7. Lhouvum, K., Balaji, S.N., Jawed, A.M and Trivedi, V* (2019). Plasmodium falciparum PFI1625c offers an opportunity to design potent anti-malarials: Biochemical characterization and testing potentials in drug discovery. Acta Tropica, 191, 116-127.
8. Raturi, V., Kumar, A., Jana, S., Bag, S.S and Trivedi, V* (2019). Virtual Screening, Molecular modelling and biochemical studies to exploit PF14_0660 as a target to identify novel anti-malarials. Letters in Drug Design & Discovery", Vol. 16, No. 4, pp 417-426 [Publisher: Bentham science Publisher].

2018

1. Nandi,S., Sharma, E., Trivedi, V and Biswas, S (2018) A Metal-Organic Framework Showing Highly Selective and Sensitive Detection of Exogenous and Endogenous Formaldehyde. Inorg. Chem. 57, 24, 15149-15157.
2. Banesh, S., Ramakrishnan V., and Trivedi, V* (2018) Mapping of Phosphatidylserine recognition region on CD36 Ectodomain. Arch Biochem Biophys. Vol 660, 15 Dec, Pages 1-10.
3. Mostakim SK., Banesh, S., Trivedi, V and Biswas, S (2018) Selective and Sensitive Sensing of Hydrogen Peroxide by a Boronic Acid Functionalized Metal-Organic Framework and its Application in Live-Cell Imaging. Inorg. Chem. 57, 23, 14574-14581.
4. Mostakim SK., Nandi, S., Singh, RK., Trivedi, V and Biswas, S. (2018) Selective Sensing of Peroxynitrite by Hf-Based UiO-66-B(OH)2 Metal–Organic Framework: Applicability to Cell Imaging. Inorg. Chem. 57, 16, 10128-10136.
5. Chowdhury, S; Balaji, SN; Subrata, M; Niranjan, M; Trivedi, V*; Iyer, P* (2018). Targeting Early Stage Amyloid Aggregates by Dipeptide Linked Perylenebisimides: Structure Activity Relationship, Inhibition and Modulation in Human CSF and Aβ1-40. ACS Appl. Bio Mater., 1 (2), pp 403–413 [Publisher: ACS].
6. Chowdhury, S; Mondal, S; Muthuraj, B; Balaji, S.N; Trivedi, V and Iyer, P (2018). Remarkably Efficient Blood-Brain Barrier Crossing Polyfluorene-Chitosan Nanoparticle Selectively Tweaks Amyloid Oligomer in CSF and Aβ1-40 ACS Omega 2018, 3, 8059-8066. [Publisher: ACS].
7. Deka, SJ., Gorai, S., Manna, D and Trivedi, V* (2018) Biochemical studies and Virtual Screening of Phytochemical reservoir from northeastern Indian plants to identify anti-cancer agents. Journal of Biologically Active Products from Nature 8 (2) pp 104 – 124. [Publisher: Taylor and Francis].
8. Nandi,S., Banesh, S Trivedi, V and Biswas, S (2018). A dinitro-functionalized metal–organic framework featuring visual and fluorogenic sensing of H2S in living cells, human blood plasma and environmental samples. Analyst 143 (6), 1482-1491.
9. Deka, SJ., Trivedi, V* (2018) Potentials of PKC in cancer progression and anticancer drug development. Curr Drug Discov Technol. Feb 2018. doi: 10.2174/1570163815666180219113614. [Epub ahead of print] [Publisher: Bentham science Publisher].
10. Das, A., Banesh, S., Trivedi, V and Biswas, S (2018). Extraordinary Sensitivity for H2S and Fe(III) Sensing in Aqueous Medium by Al-MIL-53-N3 Metal-Organic Framework: In Vitro and In Vivo Sensing Applications. Dalton Transactions, 2018, 47, 2690 - 2700.
11. Deka, SJ., Roy, A., Manna, D., and Vishal Trivedi* (2018) Integrating Virtual Screening and Biochemical Experimental approach to identify potential anti-cancer agents from Drug Databank. Journal of Bioinformatics and Computational Biology, Vol 16 (3) 1850002.
12. Saha, A., Panda, S; Pradhan, N., Kangkan,K., Trivedi, V and Manna, D. Azidophosphonate chemistry as route to a novel class of vesicle forming phosphonolipids. Chemistry–A European Journal 24 (5), 1121-1127.

2017

1. Deka, SJ., Roy, A., Ramakrishnan, V., Manna, D., and Trivedi, V* (2017). Identification of danazol as PKC modulator in breast cancer cells to induce cell-cycle dysregulation and apoptosis. Chem Biol Drug Des. 2017 Jun;89(6):953-963. [Impact Factor= 2.9] [Publisher: wiley]
2. Rajendran, R., Balaji, SN., Trivedi, V., and Chaturvedi, R. (2017) Isolation and quantification of antimalarial N-alkylamides from flower-head derived in vitro callus cultures of Spilanthes paniculata. J of Biosciences and Bioengineering, 2017 Mar 31 pii S1389-1723 [Impact Factor= 1.9] [Publisher: Elsevier].
3. Deka, SJ., Gorai, S., Manna, D., and Trivedi, V* (2017) Evidence of PKC Binding and Translocation to explain the anticancer mechanism of chlorogenic acid in breast cancer cells. Current Molecular Medicine, Vol 117, Issue 1, Page 79-89 [Impact Factor= 4.476] [Publisher: Bentham Science publisher]
4. Dalapati, R., Balaji, SN., Trivedi, V., Khamari, L and Biswas, S* (2017) A dinitro-functionalized Zr(IV)-based metal-organic framework as colorimetric and fluorogenic probe for highly selective detection of hydrogen sulphide. Sensors & Actuators: B. Chemical, 2017, 245, 1039. [Impact Factor= 4.75] [Publisher: Elsevier]
5. Paul, S., Roy, A., Deka, SJ., Panda, S., Srivastava, GN., Trivedi, V and Manna, D. (2017) Synthesis and evaluation of oxindoles as promising inhibitors to the immunosuppressive enzyme indoleamine 2,3-Dioxygenase 1. MedChemMed 8(8), 1640-1654.
6. Pradhan, N., Paul, S., Roy, A., Deka, SJ., Trivedi, V and Manna, D (2017) Identification of Substituted 1H-Indazoles as Potent Inhibitors for Immunosuppressive Enzyme Indoleamine 2,3-Dioxygenase 1. Chemistry Select 2017, 2, 5511 – 5517.
7. Nandi, S., Reinsch, H., Banesh, S., Stock, N., Trivedi, V and Biswas, S. Azide-functionalized Al(III)-based CAU-10 metal-organic framework as a fluorescent turn-on probe for the selective and sensitive detection of H2S (2017) Daltan Transduction 46 (38), 12856-12864.

2016

1. Chakraborty, A., Balaji, SN., Sahasrabuddhe, AA., and Trivedi, V* (2016) Cloning, Overexpression, Purification and Immunolocalization of PFD0975w from the malaria parasite Plasmodium falciparum. Infectious Disorders – Drug Targets, Vol 16, No. 2, Page number 000-000 (in Press).
2. Saurav Paul., Ashalata Roy; Suman Jyoti Deka; Subhankar Panda; Vishal Trivedi* and Debasis Manna* (2016). Nitrobenzofurazan Derivatives of N′-Hydroxyoximidines as potent Inhibitors of Indoleamine-2,3-Dioxygenase 1. European Journal of Medicinal Chemistry, Volume 121, 4 October 2016, Pages 364–375 [Impact Factor= 3.9] [Publisher: Elsevier].
3. Singh, M., Pakshirajan, K and Trivedi, V (2016) Photo-inactivation of Escherichia coli and Enterococcus Hirae using methylene blue and sodium anthraquinone-2-sulphonate: effect of process parameters. 3 Biotech 6 (2), 176.
4. Singh, M., Pakshirajan, K and Trivedi, V (2016) A study on combined effect of methylene blue and sodium anthraquinone-2-sulphonate on inactivation of Escherichia coli and Enterococcus Hirae. International Journal of Chem Tech Research, 9(6), pp 614-619.
5. Panda, S., Roy, A., Deka, S., Trivedi, V., Manna, D. Fused Heterocyclic Compounds as Potent Indoleamine-2,3-dioxygenase 1 Inhibitors. ACS medicinal chemistry letters 7 (12), 1167-1172 [Impact Factor= 3.35] [Publisher: American Chemical Society]
6. Deka, SJ., Narsimhan, M., Manna, D and Trivedi, V* Alkyl cinnamates exhibit PKC translocation and anticancer activity against breast cancer cells through induction of apoptosis following mitochondrial pathway. J Breast Cancer; 2016 December; 19(4): 358-371 [Impact Factor= 1.8] [Publisher: Korean Breast Cancer Society].

2015

1. A. Mehra, Gaurav Jerath, Ramakrishnan, V and Trivedi, V* (2015) Characterization of ICAM-1 Biophore to design cyto-adherence blocking peptides. J of molecular graphics and modeling, 57C:27-35. [Corresponding Author].
2. Balaji, SN., Jawed, AM*., Singh, SJ and Trivedi, V (2015) Synthesis and antimalarial potentials of curcumin analogues containing heterocyclic rings. [Accepted for publication in Arabian Journal of chemistry].
3. Malik, AH., Hussain, S., Tanwar, AS., Layek, S., Balaji, SN., Vishal Trivedi*., Iyer, PK (2015) Anionic conjugated polymer as a multi-action sensor for the sensitive detection of Cu2+, PPi, real-time ALP assaying and cell imaging. Analyst, July 7, 140(13) 4388-92. [Impact Factor= 4.10] [Publisher: Royal Society of Chemistry] [Co-Corresponding Author].
4. Muthuraj, B., Layek, S., Balaji, SN., Trivedi, V*., Iyer, PK*. Multiple Function Fluorescein Probe Performs Metal Chelation, Disaggregation and Modulation of Aggregated Aβ and Aβ-Cu Complex. ACS Chemical Neuroscience [Impact Factor= 4.36] [Publisher: ACS] [Co-Corresponding Author].

2014

1. Kuldeep, Niranjan Kumar V, Trivedi,V., Chhitar M Gupta, and Amogh Anant Sahasrabuddhe (2014) A novel actin-related protein in Leishmania regulates both the mitochondrial activity and flagellar assembly. Mol Microbiol. Dec 4. [Epub ahead of print] [Impact Factor= 4.96] [Publisher: Wiley] [COVER PAGE ARTICLE].
2. B. Muthuraj, Rohitas Deshmukh, Vishal Trivedi*, Parameswar K. Iyer* (2014) Fluorescein-based Rapid and Highly Selective “turn-on and turn-off” sensor for copper and nitric oxide generated in-vivo. Appl. Mater. Interfaces, (in press) [Corresponding Author].
3. Lhouvum, K., Kshitij, B and Trivedi, V* (2014) Molecular modeling and correlation of PFI1625-peptide models of bio active peptides with antimalarial properties Med Chem Res, in press [Impact Factor= 1.6] [Publisher: Springer] [Corresponding Author].
4. Deshmukh, R and Trivedi, V* (2014) Methemoglobin Mediated Immuno-Toxicity Modulation Of Pro-Oxidant Molecules Towards Macrophage During Malaria. PLoS One. 2014 Jul 31;9(7):e103706. [Corresponding Author].
5. Deshmukh, R* and Trivedi, V* (2014) Role of Pro-Oxidants from Infected RBCS in Disturbing Homeostasis and Pathogenesis During Malaria. Austin J Biotechnol Bioeng - Volume 1 Issue 7. [Co-Corresponding Author]

2013

1. Nag, S., Prasad, KMN., Bhowmick, A., Deshmukh, R., Trivedi, V* (2013) PfRIO-2 Kinase is a potential therapeutic target of antimalarial protein kinase inhibitors. Curr Drug Discov Technol, 10, 85-91. [Corresponding Author]
2. Deshmukh, R., Trivedi, V* (2013) Methemoglobin exposure produces toxicological effects in macrophages due to multiple ROS spike induced apoptosis. Toxicology in Vitro, 27: 16-23. [Corresponding Author]
3. Balaji, SN and Trivedi, V* (2013) Extracellular Methemoglobin Primes Red Blood Cell Aggregation in Malaria: An In-Vitro Mechanistic Study. FEBS Letters, 587, 350-357. [Corresponding Author]
4. Balaji, SN and Trivedi, V* (2013) Methemoglobin incites the primaquine toxicity through single electron oxidation and modification. J Basic Clin Physiol Pharmacol; 24(2): 105–114. [Corresponding Author]
5. Balaji, SN and Trivedi, V* (2013) Mechanism based suicidal inactivation of methemoglobin protects oxidative stress induced RBC lysis: Role of thiyl radicals of NAC in antioxidant potentials. Current Molecular Medicine, 13 (6), 1000-1009. [Corresponding Author]
6. Deshmukh, R and Trivedi, V* (2013) Pro-stimulatory role of methemoglobin in inflammation through Hemin Oxidation and Polymerization. Inflamm Allergy Drug Targets, 12 (1), 68-78. [Corresponding Author]
7. Nag, S., Chouhan, DK., Balaji, SN., Chakraborty, A., Lhouvum, K., Bal, C., Sharon, A and Trivedi, V* (2013) Comprehensive screening of heterocyclic compound libraries to identify novel inhibitors for PfRIO-2 kinase through docking and substrate competition studies. Med Chem Res, 22; 4737-4744. [Corresponding Author]
8. Lhouvum, K., Ramakrishnan, V and Trivedi, V* (2013) Insight into structural and Biochemical determinants of substrate specificity of PFI1625c: Correlation analysis of protein-peptide molecular models. J of molecular graphics and modeling, 43, 21-30. [Corresponding Author]
9. Manu S, Rohitas Deshmukh, KMN Prasad and Trivedi, V* (2013) Screening and Characterization of Antimalarial Heme Polymerase Inhibitors From Dietary Garlic Cloves. European journal of medicinal plants, 3(3) 474-484. [Corresponding Author].
10. Jain, A., Trivedi, V* (2013) Docking and Virtual screening to identify PKC agonists: potentials in anticancer therapeutics. Curr Comput Aided Drug Des. 2014 Mar;10(1):50-8.. [Corresponding Author]
11. Afsana Parween, Arnish Chakraborty, Ananda Kumar Konreddy, Harapriya Chakravarty, Ashoke Sharon, Vishal Trivedi*, Chandralata Bal* (2013) Skeletal hybridization and PfRIO-2 kinase modeling for synthesis of α-pyrone analogs as anti-malarial agent. European Journal of Medicinal Chemistry, 70, 607-612. [Corresponding Author].

2012

1. Balaji, SN and Trivedi, V* (2012). Extracellular Methemoglobin mediated early ROS spike triggers osmotic fragility and RBC destruction: An Insight into the enhanced hemolysis during malaria. Ind J Clin Biochem, 27 (2): 178-185 (Publisher: Springer) [Corresponding Author].
2. Trivedi, V* and Nag, S (2012) In Silico Characterization of Atypical Kinase, PFD0975w from plasmodium kinome: A suitable target for drug discovery. Chem Biol Drug Des. 2012 Apr;79(4):600-9. [Corresponding Author]
3. Prasad, KMN and Trivedi, V* (2012) Engineering High Resolution Horizontal Native PAGE for Proteins. International Research Journal of Biotechnology, Vol 3(4) pp 40-46. [Corresponding Author]
4. Nag, S., Prasad, KMN and Trivedi, V* (2012) Identification and screening of antimalarial Phytochemical reservoir from northeastern Indian plants to develop PfRIO-2 Kinase Inhibitor. Eur Food Res Technol, 234: 905-911. [Corresponding Author]
5. Dwivedi, A., Prasad, KMN., Trivedi, V., Iyer, P (2012) Interaction of Heme Proteins with Anionic Polyfluorene: In-sights into Physiological Effects, Folding Events and Inhibition Activity. Appl. Mater. Interfaces, 4 (11), 6371–6377.

2002-2011

1. Trivedi, V., Gupta, A., Rao, J.V.K., Saravanan, P., Rao, G.S.J., Rao, A.N., Savithri, H.S. and Subramanya, H.S. (2002) Crystal Structure of Binary and Ternary Complexes of Serine Hydroxymethyl-transferase from B.Stearothermophilus: Insights into the Catalytic Mechanism. J. Biol. Chem. 277, 17161-17169.
2. Sarkhel, S., Sharon, A., Trivedi, V., Maulik, P. R., Singh, M. M., Venugopalan, P., Ray, S. (2003) Structure-Based Drug Design : Synthesis, Crystal Structure, Biological Evalution and Docking Studies of Mono- and Bis-Benzo[b] Oxepines as Non-steroidal estrogens.Bioorg.Med.Chem.11, 5025-5033.
3. Bhavani S., Trivedi V., Ambili M., Jala V.R., Subramanya H.S., Purnima K., Appaj R.N., Savithri, H.S. (2005) Role of Lys-226 in the Catalytic Mechanism of Bacillus Stearothermophilus Serine Hydroxymethyl-transferase – Crystal Structure and Kinetic Studies. Biochemistry, 44 (18), 6929 -6937.
4. Trivedi, V ., Srivastava, K., Puri, S.K., Maulik, P.R ., Bandyopadhyay, U (2005) Purification and Biochemical Characterization of a Heme Containing Peroxidase from the Human Parasite P. falciparum. Protein Expr Purif. 37 (2) ; 154-161.
5. Trivedi, V., Chand, P., Maulik, P. R., Bandyopadhyay, U. (2005) Mechanism of Horseradish Peroxidase - Catalyzed Heme Oxidation and Polymerization (β--Hematin formation).Biochem. Biophys. Acta. 1723, 221-228.
6. Trivedi, V., Chand, P., Srivastava, K., Puri, S. K., Maulik, P. R., Bandyopadhyay, U.(2005) Clotrimazole Inhibits Hemo- Peroxidase of P. falciparum and Induces Oxidative Stress : Proposed Antimalarial Mechanism of Clotrimazole. J. Biol. Chem. 280, 41129-41136.
7. Stockinger W, Zhang, S.C., Trivedi, V, Jarzylo, L. A., Shieh, E. C., Lane, W.S., Castoreno, A. B. and Nohturfft,A (2006)Differential Requirements for Actin Polymerization, Calmodulin and Ca2+ Define Distinct Stages of Lysosome/Phagosome Targeting. Mol. Biol. Cell, 17 : 1697-1710.
8. Trivedi, V.,Zhang, S.C., Castoreno, A.B., Stockinger W, Shieh, E.C., Vyas, J.M., Frickel, E and Nohturfft, A. (2006) Immunoglobin G Signaling Activates Phagosome/Lysosome Targeting. Proc Natl Acad Sci U S A. ;103(48):18226-31.This article was selected as “Science Editor Choice article” ( Science (2006), 314, 5806 : 1661) and featured in ASBMB Today.
9. Trivedi, V, Zhang, SC, Stockinger, W and Nohturfft, A (2007). A Cell-Free Scintillation Proximity Assay for Studies on Lysosome-to-Phagosome Targeting. Science STKE, Vol 2007, Issue 392, pl3. Featured on Faculty of 1000 biology.
10. Ahmad, R., Raina, D., Trivedi, V., Ren, J., Rajabi, H., Kharbanda, S., Kufe, D. (2007) MUC1 Oncoprotein activates the IkB kinase β Complex and Constitute NF-κB Signaling. Nature Cell Biology, 9: 1419-1427 (2007). This Article appear as “Featured articles: Cancer Signaling: MUC1 mucks up Apoptosis” in Nature Signaling Updates.
11. Trivedi, V, Adrienne Boire, Boris Tchernychev, Nicole Kaneider, Andrew J Ledger, Katie O’ Callaghan, Lidija Covic & Athan Kuliopulos (2009) Platelet Matrix Metalloprotease-1 Mediates Thrombogenesis By Activating PAR1 At A Novel Cryptic Ligand Site. Cell, 137 (2), 332-43.
12. Swift, S., Xu, J., Trivedi, V., Austin, KM., Tressel, SL., Zhang, L., Covic, L., Kuliopulos, A (2010) A novel PAR1-Interactor, Bicaudal-D1, regulates G protein signaling and internalization. Identification of the microtubule associated protein, Bicaudal-D1, as a novel regulator of PAR1-G Protein Signaling. J. Biol. Chem, Feb, 17, 2010 (Epub ahead of Print).

Book Chapters

1. Shikha Jha, Rohitas Deshmukh and Vishal Trivedi (2022), “Approaches and molecular tools for targeted drug delivery in malaria infected red blood cells” Pages 149-172, Academic Press. https://doi.org/10.1016/B978-0-323-85873-1.0
2. Siddhartha Neog and Vishal Trivedi. Timir Tripathi (2022) Advances in Protein Molecular and Structural Biology Methods - 1st Edition (elsevier.com) Paperback ISBN: 9780323902649