Indian Institute of Technology Guwahati
Department of Biosciences and Bioengineering

Stem Cell and Cancer Biology Group


Semester (Jan-Apr 2018)

BT 632 Stem Cells, Cancer & Therapy

Introduction to stem cells: Types, characteristics, potency, differentiation; Stem cell isolation and culture; Embryonic, tissue specific and germ line stem cells; Induced pluripotent stem cells: direct reprogramming, transcription factors and RNAi, Stem cell specification and trans-differentiation; Stem cell niche, signaling and metabolism; Epigenetics; Cancer types, oncogenes and tumor suppressor genes; Cancer origin, progression and relapse; Cancer stem cells; Cancer and normal stem cells: common and shared pathways; Cancer microenvironment; Cancer therapy: Chemotherapy, radiation, cell and integrative therapy; Cancer multidrug resistance; Stem cells for cancer therapy; Degenerative diseases; Tissue repair and regeneration; Disease modeling and drug discovery; Ethical guidelines and issues: embryonic and induced pluripotent stem cells; Pharmacogenomics and Personalized medicine.

Reference articles: 1, 2, 3, 4,

Courses Taught

Undergraduate courses (B.Tech)
1. BT 101 Modern Biology
2. BT 208 Molecular Biology and Genetic Engineering
3. BT 303 Immunology
4. BT 308 Animal Cell Biotechnology
5. BT 301M Cellular Biotechnology

Elective courses (B.Tech, M. Tech and Ph.D)
6. BT 605 Gene Therapy
7. BT 632 Stem Cells, Cancer & Therapy
8. BT 636 Tissue Engineering and Stem Cells

Last updated: Aug 2017