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Faculty>Dr. Bithiah Grace Jaganathan>Teaching
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Teaching |
Current Semester (July-Nov 2013)
BT632 Stem Cells, Cancer and Therapy (3-0-0-6)
Introduction
to stem cells: Types, characteristics, potency, differentiation;
Stem cell isolation and culture; Embryonic, tissue specific and
germ line stem cells; Induced pluripotent stem cells: direct
reprogramming, transcription factors and RNAi, Stem cell
specification and trans-differentiation; Stem cell niche,
signaling and metabolism; Epigenetics; Cancer types, oncogenes
and tumor suppressor genes; Cancer origin, progression and
relapse; Cancer stem cells; Cancer and normal stem cells: common
and shared pathways; Cancer microenvironment; Cancer therapy:
Chemotherapy, radiation, cell and integrative therapy; Cancer
multidrug resistance; Stem cells for cancer therapy;
Degenerative diseases; Tissue repair and regeneration; Disease
modeling and drug discovery; Ethical guidelines and issues:
embryonic and induced pluripotent stem cells; Pharmacogenomics
and Personalized medicine.
Texts:
1. M. A. Hayat,
Stem Cells and Cancer Stem Cells, Vol 2, Springer, 2012.
2. N. M. Bilko, B. Fehse, W. Osterta, C.
Stocking and A.R. Zander, Stem Cells and their
potential for clinical applications, Springer, 2008.
3. R. A. Weinberg, The Biology of Cancer, Garland Science,
2007.
Lecture slides
Courses Taught
1. BT 101 Modern Biology
2. BT 208 Molecular Biology and Genetic Engineering
3. BT
303 Immunology
4. BT 308 Animal Cell Biotechnology
5.
BT 605
Gene Therapy
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